Taste Changes in Patients After Transoral Robotic Surgery for Head and Neck Cancer

Abstract

Disturbances in taste and smell frequently accompany treatment for head and neck cancer, affecting nutrition, recovery, and quality of life. This prospective observational study follows 100 adults undergoing transoral robotic surgery (TORS), with or without adjuvant therapy, to characterize the presence, severity, and duration of chemosensory changes over one year. Participants undergo structured smell and taste assessments (Sniffin’ Sticks, Taste Test 50), validated symptom surveys, and detailed chart review capturing surgical variables such as glossopharyngeal nerve handling and retractor duration. Early cohort data (n=11) highlight substantial variability in postoperative sensory changes and suggest potential contributors including nerve manipulation, surgical duration, and radiation or chemotherapy effects. As follow-up continues, the study aims to identify risk factors for prolonged dysfunction and inform counseling, surgical planning, and rehabilitative strategies for patients undergoing TORS.